Molecular mechanisms of triggering,amplifying and targeting RANK signaling in osteoclasts

• 作 者: Yukiko Kuroda Koichi Matsuo
• 机 构: LaboratoryofCellandTissueBiology
• 出 处: World Journal of Orthopedics
• 发表日期: 2012年11期
• 关键词: Receptor activator of NUCLEAR factor-κB ligand Tumor necrosis FACTOR receptor-as

Osteoclast differentiation depends on receptor activator of nuclear factor-κB(RANK)signaling,which can be divided into triggering,amplifying and targeting phases based on how active the master regulator nuclear factor of activated T-cells cytoplasmic 1(NF