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研究背景及临床问题:药源性严重过敏反应是以药物为诱因,在用药后数分钟到数小时内发生的,可累及心血管、呼吸、神经、消化系统以及皮肤黏膜组织的I型超敏反应。常见的致敏药物包括抗菌药物、非甾体抗炎药、麻醉药、造影剂等。一些疫苗由于含鸡蛋或牛奶蛋白、明胶等,或可导致严重过敏反应。近年一些国家将流感疫苗等列入全国范围内推荐预防接种项目,使得疫苗的
Research Background and Clinical Problems: Drug-induced severe allergic reactions are drug-induced, which occurs within minutes to hours after treatment and can affect type I hypersensitivity of cardiovascular, respiratory, nervous, digestive and mucocutaneous tissues reaction. Common sensitizing drugs include antimicrobials, NSAIDs, anesthetics, contrast agents and more. Some vaccines can cause severe allergic reactions due to containing egg or milk protein, gelatin, etc. In recent years, some countries include influenza vaccines and other recommended vaccination programs nationwide, making the vaccine