The translational importance of establishing biomarkers of human spinal cord injury

• 作 者: Sanam Salimi Elizei Brian K.Kw
• 机 构: InternationalCollaborationonRepairDiscoveries（ICORD）,VancouverSpineSurgeryInstitute
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2017年3期
• 关键词: 急性脊髓损伤 生物标志物 翻译 临床试验 神经功能 人类 严重程度 客观分类 spinal cord injury biomarkers cerebrosp
• 基金项目: provided by the Rick Hansen Institute, Michael Smith Foundation for Health Research, Craig Neilsen Foundation, supported by MITACS,Acknowledgments： Funding for biomarker studies was provided by the Ri

The evaluation of such novel therapies for acute spinal cord injury in clinical trials is extremely challenging.Our current dependence upon the clinical assessment of neurologic impairment renders many acute SCI patients ineligible for trials because they