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通过给妊娠１１ｄ的Ｗｉｓｔａｒ大鼠口服乙烯硫脲（ＥＴＵ），诱发胎鼠产生无肛、腰骶椎异常及体表畸形，并通过Ｘ线钼靶照像进行观察，以探讨无肛畸形伴发其他畸形的机率。结果：合并体表畸形胎鼠占无肛胎鼠的１９．５６％，伴腰骶椎异常者占６６．６％，而且发现无肛胎鼠畸形位置越高，合并腰骶椎异常及体表畸形的发生率越高，即高中低位畸形的发生率分别为５０％；３３．３％；１６．６％，这一发现对指导临床工作有重要意义。
Ethinylthiourea (ETU) was orally administered to Wistar rats on the 11th day of gestation to induce anorexia, lumbosacral vertebral anomalies and body surface abnormalities in the fetus, and the results were observed by X-ray mammography to explore the relationship between anorectal malformations Other malformations probability. Results: Fetal rats with body surface deformity accounted for 19.56% of fetus without an anus, 66.6% with abnormalities of lumbosacral vertebra, and found that the higher the anomalous position of an an an anternal fetal fetus, the abnormalities of lumbosacral vertebrae combined with body surface The higher the incidence of deformity, that is, the incidence of high and low deformity were 50%; 33.3%; 16.6%, the discovery of clinical guidance is of great significance.