论文部分内容阅读
目的观察进展性脑梗死应用丁苯酞注射液的治疗效果和不良反应。方法 80例进展性脑梗死患者,随机分为治疗组和对照组,每组40例。两组均给予基础治疗,治疗组加用丁苯酞注射液治疗。对比两组疗效及不良反应发生情况。结果治疗前两组美国国立卫生研究院卒中量表(NIHSS)评分、改良Barthel指数比较差异无统计学意义(P>0.05);治疗后治疗组NIHSS评分、改良Barthel指数明显低于对照组(P<0.05)。治疗后治疗组总有效率为82.5%,高于对照组的57.5%,差异具有统计学意义(P<0.05)。两组患者均没有出现明显药物不良反应。结论进展性脑梗死在基础治疗上加用丁苯酞注射液的治疗效果明显,不良反应少,值得临床上推广。
Objective To observe the therapeutic effect and adverse reactions of butylphthalide injection in patients with progressive cerebral infarction. Methods 80 patients with progressive cerebral infarction were randomly divided into treatment group and control group, 40 cases in each group. Both groups were given basic treatment, the treatment group with butylphthalide injection treatment. Compare the two groups of curative effects and adverse reactions. Results There was no significant difference in NIHSS score and modified Barthel index between the two groups before treatment (P> 0.05). After treatment, NIHSS score and Barthel index in treatment group were significantly lower than those in control group (P <0.05). After treatment, the total effective rate of the treatment group was 82.5%, which was higher than that of the control group (57.5%), the difference was statistically significant (P <0.05). No obvious adverse drug reactions occurred in both groups. Conclusion Progressive cerebral infarction with butylphthalide injection on the basis of the treatment of obvious effect, less adverse reactions, it is worth promoting the clinical.