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胰岛素生长因了（ＩＧＦ）是一类结构上与胰岛素部分同源并具有胰岛素样生长活性的多肽 ,有调节代谢和促进多种细胞分裂和增殖的作用。胰岛素生长因子结合蛋白（ＩＧＦＢＰ）是ＩＧＦ在循环中的特异性结合蛋白（包括ＩＧＦＢＰ-１～６）。它通过于ＩＧＦ结合成复合物来调节ＩＧ
Insulin Growth Factor (IGF) is a class of polypeptides that are structurally homologous to insulin and have insulin-like growth activity. They regulate metabolism and promote various cell divisions and proliferation. Insulin growth factor binding protein (IGFBP) is a specific binding protein (including IGFBP-1 ~ 6) of IGF in the circulation. It modulates IG by binding to the IGF complex