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Different micro needle system therapies have different advantages and characteristics.However,at present,the dominant diseases for which each therapy is appropriate are positioned relatively vaguely,and even the acupoint selections for the same disease are different.The clinical application of the dominant disease and application characteristics of each micro needle system therapy is a scientific problem that needs to be explored urgently.Based on the previous data mining study of the clinical application of auricular acupuncture,scalp acupuncture,abdominal acupuncture,eye acupuncture,wrist-ankle acupuncture,hand acupuncture,the second metacarpal bone lateral needling,facial acupuncture,mouth acupuncture and nose acupuncture,the diseases reported more in the clinical literature of each therapy were extracted to find out the same symptoms applicable to different micro needle systems.The clinical application and differences of different micro needle systems for the same disease were compared horizontally,and it demonstrated that the second metacarpal bone lateral needling,facial needle,mouth acupuncture and nose acupuncture were biased towards a partial corresponding therapeutic relationship between one part and the other part,and the eye acupuncture was biased to interfere with the whole by adjusting the function of the organs,and the auricular,scalp and abdominal needles had the both characteristics,and the wrist-malleolus acupuncture and hand acupuncture were often used in various disorders of the meridian-collateral level.The differences were researched and summarized to more accurately guide clinicians in the application of different micro needle system therapies.