【摘 要】
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Objective: To study the inhibitory effect of Gantai capsules (肝泰胶囊, GTC) on replication and expression of HBsAg and HBeAg. Methods: The 2.2.15 cell line w a
【机 构】
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Department of Pharmacy, 302 Hospital of PLA, Beijing (100039)
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Objective: To study the inhibitory effect of Gantai capsules (肝泰胶囊, GTC) on replication and expression of HBsAg and HBeAg. Methods: The 2.2.15 cell line w as chosen as a in vitro cell culture system, and by means of radioimmunoassay, t he hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) in cell cultured me dium were examined. Results: HBsAg, HBeAg values of 2.2.15 cells t reated by GTC (200 μg/ml-1200 μg/ml) were lower than those of the control. And this inhibitory effect was in a dose-dependent manner under experimental conditi o n, GTC had no cytotoxicity. Conclusion: GTC could inhibit HBV repl ication and expression.
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