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The title compound(C29H33NO2,3)was synthesized and structurally characterized by elemental analysis,IR,MS,1H-and13C-NMR and single-crystal X-ray diffraction.The crystal is of monoclinic system,space group P21with a=14.428(3),b=7.3440(15),c=22.768(5),β=95.17(3),V=2402.7(8)3,Z=4,Mr=427.56,Dc=1.182 g/cm3,F(000)=920,λ(MoKα)=0.71073,μ=0.073 mm-1,the final R=0.0670 and wR=0.1002 for 2437 reflections with I>2σ(I).Two crystallographically independent molecules with different conformations co-exist in the structure.The crystal structure is stabilized by intermolecular C Hπinteractions which make the molecules stack along the b axis.In addition,the preliminary cytotoxic assay showed that the title compound exhibited moderate inhibitory activity against KB and SW1116 cells.
The title compound (C29H33NO2,3) was synthesized and structurally characterized by elemental analysis, IR, MS, 1H-and13C-NMR and single-crystal X- ray diffraction. The crystal is of monoclinic system, space group P21with a = 14.428 (3 , b = 7.3440 (15), c = 22.768 (5), β = 95.17 (3), V = 2402.7 (8) 3, Z = 4, Mr = 427.56, Dc = 1.182 g / cm3, = 920, λ (MoKα) = 0.71073, μ = 0.073 mm-1, the final R = 0.0670 and wR = 0.1002 for 2437 reflections with I> 2σ (I). Two crystallographically independent molecules with different conformations co- exist in the structure The crystal structure is stabilized by intermolecular C Hπinteractions which make the molecules stack along the b axis. In addition, the preliminary cytotoxic assay showed that the title chemical publication moderate inhibitory activity against KB and SW1116 cells.