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Graves病(GD)是一种发病率高且易复发的重要的内分泌病。现已知甲状腺刺激性抗体(TSab)在GD中是主要的兴奋因素。作者根据TSab可与甲状腺细胞膜上TSH受体(TSHR)结合,进而激活腺苷酸环化
Graves disease (GD) is an important endocrine disease with high incidence and recurrence. Thyroid stimulating antibodies (TSabs) are now known to be the major excitatory factors in GD. According to TSab, the authors bind TSH receptor (TSHR) on the thyroid cell membrane to activate adenylate cyclase