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目的探讨急性脑梗死患者血浆D-二聚体及纤维蛋白原含量变化的临床意义。方法采用全自动血凝仪对41例急性脑梗死患者血浆D-二聚体和纤维蛋白原水平进行检测,并与对照组42例进行比较。结果脑梗死患者血浆D-二聚体及Fg含量分别为(2.49±1.21)mg/L和(3.76±0.59)g/L,均明显高于对照组[(0.26±0.17)mg/L和(2.17±0.52)g/L],差异具有显著性(P<0.05)。结论急性脑梗死患者体内存在凝血-纤溶系统异常,呈高凝状态,纤溶活性明显增高。
Objective To investigate the clinical significance of plasma D-dimer and fibrinogen in patients with acute cerebral infarction. Methods The levels of plasma D-dimer and fibrinogen in 41 patients with acute cerebral infarction were measured by automatic coagulation analyzer and compared with 42 patients in the control group. Results The levels of plasma D-dimer and Fg in patients with cerebral infarction were (2.49 ± 1.21) mg / L and (3.76 ± 0.59) g / L respectively, which were significantly higher than those in the control group [(0.26 ± 0.17) mg / 2.17 ± 0.52) g / L, the difference was significant (P <0.05). Conclusion In patients with acute cerebral infarction, coagulation - fibrinolytic system is abnormal, hypercoagulable and fibrinolytic activity is significantly increased.