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检测天津地区１１９例慢性肝病患者ＨＢＶ、ＨＣＶ标志，并对其中２８例ＨＣＶＲＮＡ阳性血清进行基因分型。结果，ＨＢＶ感染率明显高于ＨＣＶ感染率（Ｐ＜０．０５），肝癌患者中ＨＢＶ、ＨＣＶ重叠感染率明显高于慢性肝炎组（Ｐ＜０．０５）；各组均以ＨＣＶⅡ型为主。提示天津地区慢性肝病目前仍以ＨＢＶ感染为主；ＨＢＶ、ＨＣＶ重叠感染对肝癌的发生似有相加作用；ＨＣＶⅡ型感染在天津地区ＨＣＶ相关性慢性肝病中可能起主要作用。
HBV and HCV markers were detected in 119 patients with chronic liver disease in Tianjin, and 28 HCVRNA positive sera were genotyped. As a result, the HBV infection rate was significantly higher than that of HCV infection (P <0.05), and the overlapping infection rates of HBV and HCV in patients with hepatocellular carcinoma were significantly higher than those in chronic hepatitis group (P <0.05). . It is suggested that HBV infection is still the main cause of chronic liver disease in Tianjin area. HBV and HCV overlap infection may have an additive effect on the occurrence of HCC. HCV type II infection may play a major role in HCV-related chronic liver disease in Tianjin area.