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目的 :观察两种促排卵方案 :中药助孕方 +克罗米酚 (CC)和三苯氧胺 (TMX) + CC治疗常规 CC疗法不敏感的多囊卵巢综合征 (PCOS)不孕者的疗效。方法 :对 5 8例常规 CC疗法不敏感的 PCOS不孕患者随机分成两组 , 组为助孕方 + CC治疗 3 0例 , 组为 TMX+ CC治疗 2 8例。结果 : 组的妊娠率明显高于 组 (P <0 .0 5 ) ,两组的排卵率、自然流产率比较无显著性差异 (P >0 .0 5 ) , 组的黄体功能不足 (L PD)发生率、未破裂卵泡黄素化 (L UF)发生率明显低于 组 (P<0 .0 1,P<0 .0 5 ) ,两组均未发生卵巢过度刺激综合征 (OHSS)。结论 :采用中药助孕方联合 CC的促排卵方案治疗常规 CC疗法不敏感的 PCOS不孕患者优于 TMX联合 CC的促排卵方案的治疗
OBJECTIVE: To observe the effects of two kinds of ovulation induction programs: traditional Chinese medicine (TCM) plus cromolyn (CC) and tamoxifen (TMX) + CC in infertility patients with PCOS who are not sensitive to conventional CC therapy. Methods: Fifty-eight infertile women with PCOS, who were insensitive to conventional CC therapy, were randomly divided into two groups. The treatment group received 30 cases of convalescent prescription + CC and the group of 28 cases treated with TMX + CC. Results: The pregnancy rate of the group was significantly higher than that of the group (P <0.05). There was no significant difference in ovulation rate and spontaneous abortion rate between the two groups (P> 0.05) ), The incidence of unruptured follicular luteinizing (L UF) was significantly lower than that of the control group (P <0.01, P <0.05), and no ovarian hyperstimulation syndrome (OHSS) occurred in both groups. Conclusions: The treatment of infertility patients with PCOS who are not susceptible to conventional CC therapy is superior to the ovulation induction program of TMX combined with CC