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应用一种灵敏的检测DNA聚合酶反应的方法,从源自哈萨克斯坦的准葛尔毛蕊花(Verbascumsongaricum)的甲醇提取物中,筛选出2个具有抑制哺乳动物DNA聚合酶活性的已知的苯乙醇苷类的单体。取干燥的植物材料(0.5kg),用3倍量的甲醇浸提。甲醇粗提物(55g)显示DNA聚合酶抑制作用。甲醇提
Using a sensitive method for the detection of DNA polymerase reactions, two known phenethyl alcohol compounds having the activity of inhibiting mammalian DNA polymerase were screened from the methanol extract of Verbascumsongaricum originating from Kazakhstan. Monosaccharides. Dried plant material (0.5 kg) was taken and extracted with 3 times the amount of methanol. The methanol extract (55 g) showed DNA polymerase inhibition. Methanol mention