论文部分内容阅读
双氯高灭酸钠是一种非类固醇抗炎剂,通常用于治疗类风湿性关节炎等疾病。文献上曾报道过两例双氯高灭酸钠引起的血小板减少和再生障碍性贫血,但均未进行实验室检查。本文报道1例双氯高灭酸钠引起严重可逆性自身免疫性溶血和血小板减少。患者女性,71岁。入院前10天开始服用双氯高灭酸钠100mg/日,3天后感觉瘙痒,入院前两天开始发热,入院当日出现昏迷。查体:皮肤轻度黄染,无淤斑,双膝关节肿胀,右侧上下肢运动减弱,反射亢进。血红蛋白56g/l,红细胞比积14％。白细胞总数28
Diclofenac is a non-steroidal anti-inflammatory agent commonly used to treat diseases such as rheumatoid arthritis. Two cases of thrombocytopenia and aplastic anemia caused by diclofenac were reported in the literature, but none of them were laboratory tested. This article reports a case of sodium biclofenac caused severe reversible autoimmune hemolysis and thrombocytopenia. Patient female, 71 years old. 10 days before admission, taking diclofenac sodium 100mg / day, 3 days after the feeling of itching, two days before admission, fever, admission coma on the day. Examination: mild yellow skin, no ecchymosis, swelling of both knees, lower right and left lower limb movement, hyperreflexia. Hemoglobin 56g / l, hematocrit 14%. The total number of leukocytes 28