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目的 :了解医院感染高危科室的病人、护士病毒感染情况 ,以便采取有效预防措施。方法 :采用桥联酶标法直接测定 8种呼吸道病毒抗原 ,用Ellsa法测定血清 2种病毒特异性抗体 ,分别对病人 6 99人次 ,护士 316人次和正常人群 2 5 3人次对照 ,3组间进行比较、分析。结果 :病人组呼吸道病毒抗原阳性者明显高于护士组和正常对照组(P <0 .0 5 ) ,而护士组与正常对照组无明显差异 ;柯萨奇B组病毒 (CoxB)感染 ,护士组明显高于正常对照组 (P <0 .0 5 )巨细胞病毒 (CMV)感染IgG 3组间无差异 ,IgM只有少数病人阳性 ,其他 2组均阴性。结论 :呼吸道病毒感染在护士与病人之间较易控制 ,而病人间容易交叉感染 ;护士感染CoxB的危险性 (RR)为正常对照组的 2 .6 2倍 ;CMV对护士则影响不大 ;故护士在进行护理技术操作及护理病人时 ,应严格执行无菌操作及消毒隔离制度 ,对预防医院感染至关重要
Objective: To understand the infection status of patients and nurses in high-risk departments of hospital infections so as to take effective preventive measures. Methods: Eight kinds of respiratory viral antigens were measured directly by bridge-linked enzyme method, and two kinds of virus-specific antibodies were detected by Ellsa method. There were 669 patient-times, 316 nurses and 255 normal controls, respectively. Compare and analyze. Results: Patients with positive respiratory virus antigen were significantly higher in the patient group than those in the nurse group and the normal control group (P < 0.05), but there was no significant difference between the nurse group and the normal control group; Coxsackie B virus (CoxB) infection, nurse The group was significantly higher than the normal control group (P<0.05). The cytomegalovirus (CMV) infection in the IgG3 group had no difference, IgM was only positive in a few patients, and the other two groups were negative. Conclusion: Respiratory viral infection is easy to control between nurses and patients, and patients are easily cross-infected. The risk of nurses infected with CoxB (RR) is 2.62 times that of the normal control group; CMV has little effect on nurses; Therefore, the nurses should strictly perform the aseptic operation and disinfection and isolation system when carrying out nursing technical operations and nursing the patients, which is crucial for preventing nosocomial infections.