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目的:探讨干扰素应用于乙肝患者抗病毒治疗后出现的不良反应及对策。方法:选取我院于2014年2月-2015年4月收治的40例乙肝患者,对其进行干扰素α-2b治疗,观察患者出现的不良反应,并记录下来,对所产生的不良反应提出相应对策。结果:40例乙肝患者均出现了不同程度的流感样症状(92.5%)、骨髓抑制(100.0%)、消化系统症状(27.5%)以及神经系统症状(5.0%)。治疗总有效率为77.5%。结论:干扰素应用于乙肝患者会产生多种不良反应,在临床上应根据产生的不良反应作出相应的应对措施,积极预防不良反应的发生。
Objective: To investigate the adverse reactions and countermeasures of interferon after hepatitis B virus antiviral therapy. Methods: Forty patients with hepatitis B who were treated in our hospital from February 2014 to April 2015 were enrolled in this study. The patients were treated with interferon alfa-2b and their adverse reactions were observed. The adverse reactions were recorded Corresponding countermeasures. Results: All the 40 cases of hepatitis B patients showed different degrees of flu-like symptoms (92.5%), bone marrow suppression (100.0%), digestive symptoms (27.5%) and neurological symptoms (5.0%). The total effective rate was 77.5%. Conclusion: The application of interferon in patients with hepatitis B will produce a variety of adverse reactions, in the clinical response should be based on adverse reactions to make the appropriate response to actively prevent the occurrence of adverse reactions.