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新生儿旰坏死幸为少见的疾病,据报道个别病例与巨细胞病毒、风疹、ECHO等病毒感染有关,但多数病因不明。作者报告4例合并ECHO病毒11型感染的散发性新生儿肝坏死。他们的母亲在围产期无发热、呕吐、腹泻及上感等提示病毒感染的症状,但其中2例的母亲因癫痫,在孕期曾服过苯妥英钠和苯巴比妥。患儿在出生后5~6天因黄疸、纳减、嗜睡入院。 4例患儿出生时体重正常,入院时体重都比出生
Neonatal 旰 necrosis fortunate to rare disease, reported in individual cases and cytomegalovirus, rubella, ECHO and other viral infections, but most of the etiology is unknown. The authors report sporadic neonatal hepatic necrosis in 4 patients with ECHO virus infection. Their mothers did not have symptoms of viral infection during the perinatal period, including fever, vomiting, diarrhea, and flu, but 2 of the mothers had taken phenytoin sodium and phenobarbital during pregnancy because of epilepsy. Children 5 to 6 days after birth due to jaundice, satisfied, lethargy hospitalization. Four children were born with normal body weight and weighed more than they were born