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目的 :探讨麦考酚酸酯治疗儿童顽固性过敏性紫癜的疗效。方法 :14例儿童顽固性过敏性紫癜患者为治疗组 ,给予麦考酚酸酯 2 0mg·kg-1·d-1,分 2～ 3次口服。足量服用 1个月 ,继之减半量服用 1个月 ,总疗程 2个月。结果 :14例患者中13例病情不再复发 ,1例复发次数明显减少。结论 :麦考酚酸酯治疗顽固性过敏性紫癜疗效确切。
Objective: To investigate the efficacy of mycophenolate mofetil in children with refractory Henoch-Schonlein purpura. Methods: Fourteen children with refractory Henoch-Schonlein purpura were treated with 20 mg · kg-1 · d-1 mycophenolate mofetil in 2 ~ 3 orally. Take a full amount of 1 month, followed by half taking 1 month, the total duration of 2 months. Results: Of the 14 patients, 13 cases no longer relapsed and 1 case had fewer recurrences. Conclusions: Mycophenolate mofetil is effective in the treatment of refractory anaphylactoid purpura.