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七、抗生素类青霉素片:口服后大部份被胃酸和消化酶破坏,仅少量吸收,达不到有效治疗浓度。长效青霉素(苄星青霉素)片:长期服用时可能影响肠内合成维生素B类的机能,临床已不用。青霉素油剂:使用不便,吸收差,局部易硬结,血浓度低,有其它抗生素替代。青霉素软膏、青霉素眼膏:疗效差,易引起过敏和耐药,有其它抗菌药物替代。四环素(盐酸盐)各种小儿制剂、四环素(碱)各种小儿制剂、肌注四环素针:四环素能蓄积于胎儿和幼儿的骨骼和牙齿中,导致恒齿变黄,同时能使恒齿和乳齿矿质化,俗称“四环素牙”。美国儿科学会药物委
Seven, antibiotics penicillin tablets: most of the oral administration of gastric acid and digestive enzymes destroyed, only a small amount of absorption, can not reach the effective treatment concentration. Long-acting penicillin (benzathine penicillin) tablets: Long-term use may affect the function of intestinal synthesis of vitamin B class, clinical no longer. Penicillin oil: inconvenience, poor absorption, local easy to induration, low blood concentration, there are other alternative antibiotics. Penicillin ointment, penicillin ointment: poor efficacy, easy to cause allergies and drug resistance, there are other alternative antibacterial drugs. Tetracycline (hydrochloride) Various pediatric preparations, tetracycline (base) Various infants, intramuscular injection Tetracycline needle: tetracycline can accumulate in the bones and teeth of fetuses and young children, resulting in permanent teeth yellowing, while enabling permanent teeth and Milk tooth mineralization, commonly known as “tetracycline tooth.” American Academy of Pediatrics