Baicalein protects against the development of angiotensin II-induced abdominal aortic aneurysms by b

• 作 者: Fang Wang Houzao Chen Yunfei Y
• 机 构: StateKeyLaboratoryofMedicalMolecularBiology,DepartmentofCardiology
• 出 处: 中国科学：生命科学英文版
• 发表日期: 2016年9期
• 关键词: 血管紧张素II MAPK 动脉瘤 黄芩素 信号转导 p38 JNK 丝裂原活化蛋白激酶 baicalein abdominal aortic aneurysm
• 基金项目: supported by the National Natural Science Foundation of China（31571193,81422002,91339201）

An abdominal aortic aneurysm(AAA) is a permanent, localized dilatation of the abdominal aorta. In western countries, the morbidity of AAA is approximately 8%. Currently, pharmacotherapies for AAA are limited. Here, we demonstrate that baicalein(BAI), the