论文部分内容阅读
为观察DDD起搏对病窦综合征 (SSS)患者阵发性心房颤动 (AF)的远期影响 ,对 6 6例合并阵发性AF的病窦综合征患者 ,择期置入DDD永久起搏器 ,术后进行临床、心电图、2 4h动态心电图的定期随访 ,观察比较DDD起搏器置入术前 1年、术后 1,2 ,5年的阵发性AF发作频率以及发作持续时间。结果 :所有患者起搏器置入后随访 1～ 2年阵发性AF发作的频率及发作的时间较起搏器置入前显著减少 (T0 -1146 ,T0 -2 137,P均 <0 .0 5 ) ;术后随访 5年时阵发性AF发作的频率及发作的时间较术后 1～ 2年显著增加 (T1-5143,T2 -512 1,P均 <0 .0 5 )。所有患者术后无心力衰竭、血栓栓塞发生。结论 :DDD起搏对SSS并发的阵发性AF的发生有抑制及预防作用 ,这种影响在起搏器治疗近中期最为显著 ,远期疗效不肯定尚需进一步临床观察。
To observe the long-term effects of DDD pacing on paroxysmal atrial fibrillation (AF) in patients with sick sinus syndrome (SSS), 66 patients with sick sinus syndrome complicated with paroxysmal AF were enrolled in DDD permanent pacing The patients were followed up for clinical, electrocardiogram and 24 hours ambulatory electrocardiogram. The frequency of paroxysmal AF and the duration of paroxysmal AF were compared between 1 year before operation and 1,2 and 5 years after operation. Results: The frequency of episodes of paroxysmal AF and the duration of the episodes were significantly lower than those before the pacemaker was inserted (P <0.01) in all patients with one or two years after follow-up. 0 5). The frequency of episodes of paroxysmal AF and the duration of attack at 5 years after follow-up were significantly increased from 1 to 2 years after operation (T1-5143, T2 -5121, P <0.05). All patients without heart failure, thromboembolism occurred. Conclusions: DDD pacing has an inhibitory and preventive effect on the occurrence of paroxysmal AF complicated by SSS. This effect is the most obvious in the near and mid-term of pacemaker treatment. The long-term curative effect is not yet confirmed and further clinical observation is needed.