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目的:对麻疹发病与麻疹疫苗接种的病例进行对照,分析麻疹减毒活疫苗效力与麻疹发病之间的关系。方法:选取2013年01月-2013年12月于我景东县疾控中心(下文简称:我县疾控中心)调查的45例麻疹患者为研究组,并选取45例未患麻疹病的健康人作为对照组,比较麻疹发病与麻疹疫苗接种的病例。结果:麻疹患者及正常人免疫史主要来源于家长回忆、预防接种卡、预防接种证及其他,两组免疫史来源差异无统计学意义(P>0.05)。研究组麻疹疫苗的接种率明显低于对照组,MV效力为96.12%,VE可信区间在92.6%-96.9%之间;两组差异具有统计学意义(P<0.05)。结论:今后需要进一步加强儿童常规免疫接种,最大限度地提高麻疹减毒活疫苗的接种率,并在此基础上积极地开展麻疹减毒活疫苗复种及麻疹减毒活疫苗强化免疫,主要目的在于为常规免疫存在的不足进行补充。
Objective: To compare the incidence of measles and measles vaccination cases, and to analyze the relationship between the efficacy of live attenuated measles vaccine and the incidence of measles. Methods: 45 measles patients selected from January 2013 to December 2013 in our Jingdong CDC (hereinafter referred to as “CDC”) were selected as research group and 45 healthy people without measles As a control group, the incidences of measles and measles vaccination were compared. Results: The immunization history of measles patients and normal people mainly came from parents’ recall, vaccination card, vaccination card and others. There was no significant difference in the origin of immunization history between the two groups (P> 0.05). The vaccination rate of measles vaccine in the study group was significantly lower than that of the control group. The MV efficacy was 96.12% and the VE confidence interval was between 92.6% and 96.9%. The differences between the two groups were statistically significant (P <0.05). Conclusion: In the future, it is necessary to further strengthen routine immunization of children so as to maximize the vaccination rate of attenuated live attenuated measles vaccine. On the basis of this, active vaccination of live attenuated measles vaccine and live attenuated measles vaccine are carried out. The main purpose is To supplement the deficiencies of conventional immunization.