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目的探讨青少年胸部Askin瘤的影像表现。方法对1例青少年Askin瘤的临床表现、病理学特点及影像资料进行分析,并结合文献进行复习。结果 Askin瘤好发于儿童和青少年,女性多见,瘤体一般较大,包膜不完整或无包膜,CT表现单侧胸腔内巨大肿块,可累及胸膜、膈肌等,CT能清晰显示肿瘤的内部密度、肿瘤的范围、显示肺内的转移、肿块与肺、胸膜、纵隔的关系以及肋骨破坏的情况。病理学特点瘤细胞由小圆细胞构成,有菊形团;免疫表型:CD99、NSE、VIM、S100阳性;电镜下观察到肿瘤细胞胞浆内神经内分泌颗粒。结论 Askin瘤临床与影像学表现有一定的特点,但均为非特征性表现,最后诊断须依靠病理、免疫组化及电镜检查。
Objective To investigate the imaging findings of Askin’s tumor in young chest. Methods The clinical manifestations, pathological features and imaging data of 1 young adolescent Askin tumor were analyzed and reviewed with the literature. Results Askin’s tumor was common in children and adolescents. It was more common in women. The tumor size was generally larger, with incomplete or non-enveloped CT. CT showed unilateral pleural masses with pleural and diaphragmatic involvement. CT could clearly show the tumor The internal densities, the extent of the tumor, the metastases in the lungs, the relationship of the masses to the lungs, pleura, mediastinum, and the destruction of the ribs. Pathological features of tumor cells from small round cells, with chrysanthemum; Immunophenotype: CD99, NSE, VIM, S100 positive; electron microscopy was observed within the cytoplasm of tumor cells neuroendocrine granules. Conclusion The clinical and imaging findings of Askin’s tumor have some characteristics, but they are non-characteristic manifestations. The final diagnosis depends on the pathology, immunohistochemistry and electron microscopy.