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肾病综合征(NS)是儿科的常见病,典型表现为大量蛋白尿、低蛋白血症、高脂血症以及不同程度的水肿。NS患者同时具备以下任何一项者为难治性肾病综合征(RNS):(1)激素抵抗。初发或复治患者,经用糖皮质激素治疗8周无效。(2)激素依赖。使用激素治疗有效,但在药物减量时复发。(3)频复发。半年内复发2次以上,或1年内复发超过3次。现代医学多采用激素、免疫抑制剂等联合治疗,疗效不佳,且副作用较大,易复发[1]。临床研究表明,中医药参与治疗RNS可以获得比单纯应用西药治疗
Nephrotic syndrome (NS) is a common pediatric disease, typically manifested as massive proteinuria, hypoproteinemia, hyperlipidemia, and varying degrees of edema. Patients with NS also have refractory nephrotic syndrome (RNS) with either of the following: (1) Hormone resistance. Initial or retreatment patients treated with glucocorticoids for 8 weeks is invalid. (2) hormone dependence. Hormone therapy is effective, but relapse occurs when the drug is reduced. (3) frequency recurrence. Relapse more than 2 times within six months, or more than 3 times within 1 year. Modern medicine and more use of hormones, immunosuppressive agents and other joint treatment, poor efficacy, and side effects, easy to relapse [1]. Clinical studies have shown that Chinese medicine treatment of RNS can be obtained than the simple application of western medicine