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当细胞接受到生理或病理信号时,会做出相应的反应从而最大可能地维护生命体的正常功能。细胞死亡是这类反应中的一个,它的调控在个体发育及维护生命个体正常功能上起着很大的作用。因此,细胞死亡的机制是现代生物学的一个研究热点。细胞的死亡可以以不同的方式进行。细胞的死亡方式不同往往会导致不同的生物学效应。厦门大学韩家淮实验室近期的工作发现细胞的死亡方式之间可以转换,而此转换受能量代谢调控的影响。
When a cell receives a physiological or pathological signal, it responds accordingly to maximize the normal function of the living being. Cell death is one of such reactions, and its regulation plays an important role in the development of individuals and in the maintenance of the normal function of life individuals. Therefore, the mechanism of cell death is a hot topic in modern biology. Cell death can occur in different ways. Different ways of cell death often lead to different biological effects. Recently, Han Jia-Huai Laboratory, Xiamen University, found that cell death patterns can be switched between, and this conversion is affected by the regulation of energy metabolism.