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本文对我院心内科在1991-1995年间施行静脉溶栓治疗的100例急性心肌梗塞病例的临床资料进行了分析总结,结果:血管通畅率61%,其中尿激酶57%,链激酶71%;总死亡率6%,其中血管再通组和未通组分别为1.6%或12.8%(P<0.001);再通组的心衰和严重室性心律失常的发生率均明显低于未通组,且左室射血分数明显高于未通组;溶栓在梗塞发作6小时内开始者其通畅率远远大于6-12小时者,我们认为在严格排除禁忌证,确定适应证后,溶栓治疗应尽早开始;同时严密心电血压监测,以增加成功率和安全性。
In this paper, clinical data of 100 cases of acute myocardial infarction treated by intravenous thrombolysis in the Department of Cardiology of our hospital during 1991-1995 were analyzed and summarized. Results: Vascular patency rate was 61%, including 57% of urokinase and 71% of streptokinase; The overall mortality rate was 6%, of which 1.6% or 12.8% in the recanalization group and the non-recanalization group, respectively (P <0.001). The incidence of heart failure and severe ventricular arrhythmia in the recanalization group was Significantly lower than the non-pass group, and left ventricular ejection fraction was significantly higher than the failed group; thrombolytic initiation within 6 hours of onset of the patency rate is much greater than 6-12 hours, we believe that the strict exclusion of contraindications, After identifying indications, thrombolytic therapy should start as soon as possible; at the same time close monitoring of ECG, to increase the success rate and safety.