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近百年来就有人注意到,从事偶氮染料(品红)生产的工人膀胱癌发生率明显增加。但直到近几十年才在动物身上证实了合成偶氮染料的芳香胺(2-萘胺等)对膀胱的致癌作用。大量流行病学调查资料表明,膀胱肿瘤的高发与职业性接触偶氮染料密切相关,并认为芳香胺对职业性膀胱癌的发生起重要作用。近来发
It has been noted for nearly a century that the incidence of bladder cancer in workers engaged in the production of azo dyes (magenta) has increased significantly. However, it has not been confirmed in animal bodies until recently that carcinogenic effects of the azo dyes (aromatic amines such as 2-naphthylamine and the like) on the bladder have been confirmed in animals. A large number of epidemiological survey data show that the high incidence of bladder cancer and occupational exposure to azo dyes are closely linked and that aromatic amines on the occurrence of occupational bladder cancer play an important role. Recently sent