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近年来,无论我国或西方国家老年人口比例都有增长趋势。老年人心脏病流行率高达50％,直接死于充血性心力衰竭(CHF)者约占6～15％。国内一组100例老年CHF临床分析,病死率高达33％。难治性CHF渐受到重视。 随年龄增长,老年人心肌细胞核两极多有褐色素脂肪沉积和淀粉样退行变趋势,起搏细胞数量逐渐减少,75岁时较20岁者减少>10％。心脏遭受长期过重血液动力学负荷或原发性收缩力障碍时,主要依靠三个内在机理维持休息时正常心排血量(CO):(1)心室
In recent years, the proportion of the elderly in our country or in the west has been on the increase. The prevalence of heart disease in the elderly is as high as 50%, with direct death from congestive heart failure (CHF) accounting for 6-15%. A group of 100 cases of elderly CHF clinical analysis, case fatality rate as high as 33%. Refractory CHF is getting more attention. With age, there were more brown fat deposits and amyloid retrograde changes in the nuclei of the elderly myocardial cells, and the number of paced cells decreased gradually, which was reduced by> 10% at 75 years of age compared with that of the 20-year-olds. When the heart suffers from long-term overweight hemodynamic loading or primary contractile disorders, it mainly relies on three intrinsic mechanisms to maintain normal cardiac output at rest (CO): (1) Ventricular