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目的 :探讨两种国产透明质酸钠 (“其胜”和“爱维”) (hyaluronicacid ,HA)在眼科手术中各自的适用指征。方法 :对 85例老年性白内障和 4 5例角膜穿孔伤分别行白内障超声乳化吸除及人工晶体植入术、角膜修补术 ,按术中应用不同的HA ,随机分为A组 (“爱维”HA组 )和B组 (“其胜”HA组 )。观察两组眼内炎症反应、HA前房代谢率和粘滞性的差异。结果 :术后第一天A组 5例 ( 1 1 9% )B组 1 2例( 2 7 3% )眼内炎症明显 ;术中B组HA粘滞性大于A组 ;角膜修补术后第四天 ,A组 5例 ( 2 2 7% ) ,B组1 2例 ( 52 2 % )房水活动状态恢复 ,两组差异有显著性 (P <0 0 5)。结论 :“爱维”HA具有较好的生物相容性 ,可适用于各种常规眼科手术 ;“其胜”HA具有较高的粘弹性 ,适用于一些能起到眼内正压推挤作用的手术。
Objective: To investigate the applicable indications of two domestic sodium hyaluronate (HAQ) and HA (hyaluronic acid) in ophthalmic surgery respectively. Methods: 85 cases of senile cataracts and 45 cases of corneal perforation were performed phacoemulsification and intraocular lens implantation, corneal repair, according to the application of different HA, were randomly divided into group A (“Ai Wei ”HA group“) and group B (”its victory“ HA group). The intraocular inflammation, HA anterior chamber metabolic rate and viscosity differences were observed. Results: On the first day after operation, 12 cases (273%) in Group A had obvious intraocular inflammation in 5 cases (119%) of Group A, HA in Group B was more than those in Group A, In four days, the activity of aqueous humor in group A recovered (12 27%) and in group B 12 (52 2%), the difference was significant (P <0.05). Conclusion: ”Aiwei“ HA has good biocompatibility and can be applied to all kinds of routine ophthalmic surgeries. ”Its advantage" HA has higher viscoelasticity and is suitable for some patients who can play a role of intraocular pressure pushing Surgery.