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目的 探讨原发性胃恶性淋巴瘤的诊断、治疗及预后问题。方法 回顾性分析我院 41例的临床、病理及随访资料。生存率用寿命表法计算 ,显著性检验用卡方检验。结果 本组病例主要症状为腹部疼痛不适 (37/4 1)、消化道出血 (13/4 1)和腹部肿块 (12 /4 1)。 41例均为非何杰金氏淋巴瘤 ,其中MALT淋巴瘤 8例。术前诊断率2 9.3% ,手术切除率 90 % ,病例随访率 82 .9% ,1年、5年、10年生存率分别为 70 .6 %、5 2 .9%、38.2 %。临床分期(P <0 .0 1)、肿瘤大小 (P <0 .0 1)、组织学分级 (P <0 .0 5 )、浆膜累及 (P <0 .0 5 )和手术切除 (P <0 .0 5 )与预后有关。结论 手术切除是诊断、临床分期和治疗的主要方法 ;临床分期、恶性程度和根治手术是患者的预后因素 ;巨块型和浆膜累及者预后较差
Objective To investigate the diagnosis, treatment and prognosis of primary gastric malignant lymphoma. Methods The clinical, pathological and follow-up data of 41 cases in our hospital were retrospectively analyzed. Survival rate calculated using life table, significant test using chi-square test. Results The main symptoms of this group were abdominal discomfort (37/41), gastrointestinal bleeding (13/4 1) and abdominal mass (12/41). All 41 cases were non-Hodgkin’s lymphoma, of which 8 were MALT lymphoma. The preoperative diagnosis rate was 23.3%, the surgical resection rate was 90%. The follow-up rate was 82.9%. The 1-year, 5-year and 10-year survival rates were 70.6%, 52.29% and 38.2% respectively. The clinical stage (P <0.01), tumor size (P <0.01), histological grade (P <0.05), serosa involvement (P <0.05) and surgical resection <0. 05) and prognosis. Conclusions Surgical resection is the main method of diagnosis, clinical staging and treatment. The clinical stage, malignancy and radical operation are the prognostic factors of patients. The prognosis of patients with massive and serosal involvement is poor