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目的评价见肿消巴布剂治疗癌性疼痛的的疗效及安全性。方法 80例癌痛患者随机分为观察组和对照组。对照组给以西医常规治疗(主要是三阶梯止痛),观察组在西医常规治疗的同时加用见肿消巴布剂外敷。观察并比较两组疼痛程度、疼痛缓解有效率和治疗前后生活质量改善情况。结果两组患者治疗前后疼痛程度比较:用药后第3、7、14、28日NRS评分与用药前比较,均有非常显著性差异(P<0.01);第7、14、28日组间比较,有显著性差异(P<0.05或P<0.01)。两组患者疼痛缓解有效率的比较:观察组疼痛缓解总有效率明显升高,两组比较有显著性差异(P<0.05)。两组患者治疗前后生活质量改善情况:治疗前后KPS评分比较均有非常显著性差异(P<0.05,P<0.01),且观察组KPS评分高于对照组(P<0.05)。结论见肿消巴布剂可以提高止痛药物的止痛效果,且远期效果更明显,还可以进一步提高癌症患者的生活质量。
Objective To evaluate the efficacy and safety of swollen poultice in the treatment of cancer pain. Methods 80 patients with cancer pain were randomly divided into observation group and control group. The control group was treated with conventional Western medicine (mainly three-step analgesic pain). The observation group was treated with topical western medicine and topical vaginal poultice. The degree of pain, the effective rate of pain relief and the improvement of quality of life before and after treatment were observed and compared. Results The pain scores of two groups before and after treatment were compared: the NRS scores on the 3rd, 7th, 14th and 28th days after treatment were significantly different from those before treatment (P <0.01); on the 7th, 14th and 28th days , There was significant difference (P <0.05 or P <0.01). Efficacy of pain relief in both groups were compared: the total effective rate of pain relief in the observation group was significantly higher than that of the control group (P <0.05). The improvement of quality of life before and after treatment in both groups was significant (P <0.05, P <0.01). The KPS score in the observation group was higher than that in the control group (P <0.05). Conclusion swollen pudding see analgesic drugs can enhance the analgesic effect, and long-term effect is more obvious, but also can further improve the quality of life of cancer patients.