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目的:试图阐明胰岛素抵抗(IR)与脑卒中的关系。方法:对16例动脉粥样硬化血栓形成性脑梗塞患者,9例腔隙性脑梗塞患者,9例脑出血患者和16例对照。测定空腹血糖和胰岛素浓度,计算胰岛素敏感性指标,比较各组的胰岛素敏感性。结果:动脉粥样硬化血栓形成性脑梗塞的胰岛素敏感性显著低于腔隙性脑梗塞组(P＜0.05)。结论:IR可能与动脉粥样硬化血栓形成性脑梗塞的发病有关。
Objective: To elucidate the relationship between insulin resistance (IR) and stroke. Methods: Sixteen patients with atherothrombotic cerebral infarction, nine patients with lacunar infarction, nine patients with cerebral hemorrhage and 16 controls. Fasting blood glucose and insulin concentrations were measured, insulin sensitivity indicators were calculated, and insulin sensitivity of each group was compared. Results: The insulin sensitivity of atherothrombotic cerebral infarction was significantly lower than that of lacunar infarction group (P <0.05). Conclusion: IR may be related to the pathogenesis of atherothrombotic cerebral infarction.