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研究了正常人和有、无口渴多饮史的糖尿病患者各６例的加压素释放、渴感与血浆渗透压（血渗）的关系。所有受试者均以每分钟０．０６ｍｌ／ｋｇ体重的速度静脉滴注５％ＮａＣｌ溶液２小时，于滴注前、后测定血浆葡萄糖（血糖）、血浆钠、血渗及血浆加压素水平和渴感程度。结果表明静脉滴注５％ＮａＣｌ可使三组血渗明显增高、血浆加压素水平增高及渴感增强。但糖尿病组血浆加压素水平增高幅度明显低于正常组，糖尿病两组之间差别不明显。无口渴多饮史的糖尿病病人渴感增强程度明显不如有口渴多饮史的糖尿病病人及正常人，后两组差别不明显。说明糖尿病病人加压素储备减少，无口渴多饮史的病人存在渴感减退。
The relationship between vasopressin release, thirst and plasma osmolality (blood osmolality) in 6 normal subjects and in diabetic patients without history of thirsty drinking and drinking was studied. All subjects were intravenously dripped 5% NaCl solution at 0.06ml / kg body weight per minute for 2 hours. Plasma glucose, And thirsty degree. The results showed that intravenous infusion of 5% NaCl significantly increased blood-3 levels, increased plasma vasopressin level and increased thirst. However, the increase of plasma vasopressin level in diabetic group was significantly lower than that in normal group, and the difference between the two groups was not obvious. Diabetes patients without history of thirsty drinking history increased significantly thirsty diabetes than those with history of thirsty drinking history and normal people, the difference was not obvious after the two groups. Description of diabetic patients with reduced vasopressin reserves, no history of thirsty drinking history of patients there thirst decline.