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25年前进行第一例肾移植时,排斥反应曾被认为只不过是由单—淋巴细胞克隆介导的简单过程。过去十年来的研究已表明,排斥反应是有许多淋巴细胞亚群和记忆细胞参与的十分复杂的过程。一、同种抗原人类白细胞抗原(HLA)是移植的主要障碍。在同胞间肾移植中
When the first kidney transplant was performed 25 years ago, rejection was thought to be simply a simple process mediated by mono-lymphocyte cloning. Research over the past decade has shown that rejection is a complex process involving many lymphocyte subsets and memory cells. First, the alloantigens Human leukocyte antigen (HLA) is a major obstacle to transplantation. In siblings kidney transplantation