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为探讨线粒体(mt)DNA4977bp大片段缺失和肿瘤间的相关性,我们检测了mt DNA4977bp大片段缺失在肺癌组织、癌旁正常组织及非癌患者肺组织的分布频率,并分析了缺失与患者年龄、吸烟因素、肺癌组织病理类型等的关系。一、材料和方法1.病例资料:37例肺癌组织和37例癌旁肺组织标本均
To investigate the relationship between mitochondrial DNA4977bp deletion and tumorigenicity, we examined the distribution of mt DNA4977bp deletion in the lung tissues of lung cancer, adjacent normal tissue and noncancerous patients, and analyzed the relationship between the deletion and patient age , Smoking factors, lung cancer histopathology and so on. First, the material and methods 1 case data: 37 cases of lung cancer and 37 cases of adjacent lung tissue samples