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目的研究糖化血红蛋白(HbA1c)水平与妊娠期糖尿病患者并发症及妊娠结局的相关性。方法选取2014年1月-2016年1月该院收治的90例妊娠期糖尿病患者,根据患者HbA1c水平分为3组,每组各30例(A组:HbA1c<6%;B组:6%≤HbA1c<7%;C组:HbA1c≥7%),对3组孕妇妊娠并发症以及妊娠结局情况进行对比分析。结果 A组羊水过多、胎膜早破、妊娠期高血压疾病以及产后感染等并发症发生率最低,其次是B组和C组,差异有统计学意义(P<0.05);A组巨大儿、早产儿、新生儿低血糖以及宫内窘迫发生率最低,其次是B组和C组,差异有统计学意义(P<0.05);A组产后疲劳、抑郁和焦虑评分最低,其次是B组和C组,差异有统计学意义(P<0.05)。结论 HbA1c水平影响妊娠期糖尿病患者并发症发生,并且影响妊娠结局和产妇预后。
Objective To study the relationship between the level of HbA1c and the complication and pregnancy outcome in gestational diabetes mellitus. Methods Ninety patients with gestational diabetes mellitus admitted to our hospital from January 2014 to January 2016 were divided into 3 groups according to the level of HbA1c in 30 patients (group A: HbA1c <6%; group B: 6% ≤HbA1c <7%; group C: HbA1c≥7%). The pregnancy complications and pregnancy outcomes were compared among the three groups. Results A group of oligohydramnios, premature rupture of membranes, pregnancy-induced hypertension and postpartum infection complications such as the lowest incidence, followed by B and C group, the difference was statistically significant (P <0.05); A group of giant children , Preterm infants, neonatal hypoglycemia and intrauterine distress rate was the lowest, followed by the B group and C group, the difference was statistically significant (P <0.05); A group postpartum fatigue, depression and anxiety score the lowest, followed by the B group And C group, the difference was statistically significant (P <0.05). Conclusion The level of HbA1c affects the complications of gestational diabetes mellitus and affects the outcome of pregnancy and the prognosis of maternal.