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目的研究2型糖尿病病人微量白蛋白尿的危险因素。方法对93例伴或不伴高血压的2型糖尿病病入进行动态血压监测,同时测定尿白蛋白排泄率、血糖、血脂等,分析其相互关系,以是否有微量白蛋白尿为因变量,拟合Logistic回归。结果血压昼夜节律异常和血压水平增高是2型糖尿病病人微量白蛋白尿发生的主要危险因素,血清甘油三酯水平升高、体重指数的增加也有增加微量白蛋白尿发生的趋势。结论长期血糖、血压、血脂控制不良将导致发生2型糖尿病病人微量白蛋白尿。
Objective To study the risk factors of microalbuminuria in type 2 diabetic patients. Methods Ninety-three patients with type 2 diabetes mellitus with or without hypertension were monitored for ambulatory blood pressure, urinary albumin excretion rate, blood glucose and blood lipids were measured at the same time. The correlation was analyzed to find out whether microalbuminuria was the dependent variable. Fit Logistic regression. Results The abnormal circadian rhythm of blood pressure and the increase of blood pressure were the main risk factors of microalbuminuria in patients with type 2 diabetes. The serum triglyceride level increased and the increase of body mass index also had the tendency of increasing microalbuminuria. Conclusion Long-term blood glucose, blood pressure, dyslipidemia will lead to the occurrence of type 2 diabetes patients with microalbuminuria.