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目的：观察比索洛尔对急性心肌梗死（ＡＭＩ）后无症状性心肌缺血的治疗作用。方法：用随机对照方法将７３例ＡＭＩ患者分为比索洛尔治疗组和对照组，采用２４小时动态心电图记录用药后无症状性心肌缺血发作情况，同时行核素心功能检查。结果：比索洛尔组缺血持续时间为１．５（０～２７．５）ｍｉｎ／２４ｈ，缺血总负荷为２．４（０～４６．５）ｍｉｎ／ｍｍ；对照组缺血时间为６．５（０～３９）ｍｉｎ／２４ｈ，缺血总负荷为１１．８（０～６９．６）ｍｉｎ·ｍｍ，两组比较，Ｐ＜０．０５。核素心功能检查比较两组差异无显著性。结论：比索洛尔能有效地治疗ＡＭＩ后无症状性心肌缺血。
Objective: To observe the therapeutic effect of bisoprolol on asymptomatic myocardial ischemia after acute myocardial infarction (AMI). Methods: A total of 73 AMI patients were divided into bisoprolol treatment group and control group by randomized controlled trial. Asymptomatic myocardial ischemia was recorded by 24-hour ambulatory electrocardiogram. At the same time, cardiac function tests were performed. RESULTS: The duration of ischemia in bisoprolol group was 1.5 (0-27.5) min / 24h and the total ischemic load was 2.4 (0-46.5) min / mm. The ischemic time in the control group was 6.5 (0-39) min / 24h, the total ischemic load was 11.8 (0-69.6) min · mm, P <0.05. There was no significant difference between the two groups in the radionuclide function test. Conclusion: Bisoprolol can effectively treat asymptomatic myocardial ischemia after AMI.