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目的比较3种不同配伍的氯胺酮在小儿斜视矫正术中的应用。方法ASAⅠ～Ⅱ级眼外肌矫正术的患儿40例。随机分成3组,M组咪唑安定1mg/kg;P组丙泊酚3～9mg/(kg·h);MP组咪唑安定1mg/kg丙泊酚3～9mg/(kg·h)。3组患儿视手术需要追加氯胺酮0.5～1mg/kg。记录手术时间,苏醒时间,氯胺酮总量。术中5min,20min时HR、Bp的变化。结果MP组患儿氯胺酮总量显著少于M组、P组(P<0.01)。苏醒时间短于M组、P组(P<0.05)。术后随访M组发生恶心呕吐例数多于P组、MP组(P<0.05)。结论氯胺酮、咪唑安定、丙泊酚合用于小儿斜视矫正术为较好配伍。
Objective To compare the application of three kinds of ketamine with different compatibility in pediatric strabismus surgery. Methods 40 cases of children with ASA Ⅰ ~ Ⅱ extraocular muscle. Patients in group M were treated with midazolam 1 mg / kg and propofol 3 ~ 9 mg / (kg · h) in group M respectively. Midazolam 1 mg / kg and propofol 3-9 mg / (kg · h) were administered to MP group. 3 groups of children need surgery to add ketamine 0.5 ~ 1mg / kg. Record operation time, recovery time, total ketamine. Intraoperative 5min, 20min HR, Bp changes. Results The total amount of ketamine in MP group was significantly less than that in M group and P group (P <0.01). Recovery time shorter than the M group, P group (P <0.05). Postoperative follow-up M group nausea and vomiting cases more than P group, MP group (P <0.05). Conclusion Ketamine, midazolam, propofol combined strabismus correction for children with better compatibility.