论文部分内容阅读
铊～201心肌灌注显像(~(201)TlMPI)是70年代中期才应用于诊断缺血性心脏病的一种非创伤性方法。但是仍有19～39％的假阴性。1978年GouId首次将药物应激法——潘生丁-铊-201心肌灌注显像(DP-~(201)TlMPI)用于检测冠心病,其敏感性、特异性等于或优于运动~(201)TlMPI。 方法学 (1)试验前2天停用DP、氨茶硷类药物,禁饮茶、咖啡等饮料。(2)使用DP剂量为0.14～0.15mg/kg·min~(-1),以注射泵匀速注射4min。试验前、中记录心电图和观察血压的变化。备用氨茶硷以拮抗DP注射所引起的副反应。(3)注射完DP4min后,再注入~(201)T155.5～74.0×10~6Bq(1.5～2.0mCI),用γ闪烁照相机立即进行前后位、左前斜位、左侧位心肌显像,为初始药物相。3～4h后再摄与前相同体位的延迟再分布相。(4)若注入DP后引起心绞痛等副作用,则用
Thallium ~ 201 myocardial perfusion imaging (~ (201) TlMPI) is a non-invasive method used to diagnose ischemic heart disease in the mid-1970s. But there are still 19 to 39% false negatives. In 1978 GouId for the first time the drug stress method - dipyridamole - thallium -201 myocardial perfusion imaging (DP- ~ (201) TlMPI) for the detection of coronary heart disease, its sensitivity, specificity equal to or better than exercise ~ (201) TlMPI. Methodology (1) 2 days before the trial disable DP, aminophylline drugs, ban tea, coffee and other beverages. (2) The dosage of DP was 0.14 ~ 0.15mg / kg · min ~ (-1), and the injection pump was used for 4min. Before and after the test record in the ECG and observe the changes in blood pressure. Alternate aminophylline to antagonize DP injection caused by side effects. (3) After injecting DP4min, injecting ~ (201) T155.5 ~ 74.0 × 10 ~ 6Bq (1.5 ~ 2.0mCI), using γ scintigraphy camera immediately before and after, left anterior oblique, left myocardial imaging, For the initial drug phase. 3 ~ 4h and then taken the same position before the delayed redistribution phase. (4) If injected into the DP cause angina and other side effects, then use