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目的:探讨肺表面活性物质(PS)单次和多次气道注入后对早产儿视网膜病(ROP)发生率的影响。方法:根据早产儿有无使用肺表面活性物质和使用的次数分为PS单次组、PS多次组和对照组,每周对患儿进行眼底检查,记录各组患儿发生ROP情况,比较各组ROP发生率和ROP程度的差异。结果:ROP的发生率为2.92%,PS单次组、PS多次组和对照组之间的ROP发生率和严重程度的差别无统计学意义。结论:随着对ROP日益重视,ROP的发生率有所降低,PS对早产儿ROP的发生并无显著性影响。
Objective: To investigate the effect of pulmonary surfactant (PS) single and multiple airway infusions on the incidence of retinopathy of prematurity (ROP). Methods: According to the presence or absence of pulmonary surfactant in preterm infants and the use of the number of divided into PS single group, PS multiple groups and control group, the fundus examination every week to record the occurrence of ROP in each group of children, compare Differences in the incidence of ROP and ROP in each group. Results: The incidence of ROP was 2.92%. There was no significant difference in the incidence and severity of ROP between PS single group, multiple PS group and control group. Conclusion: With the increasing emphasis on ROP, the incidence of ROP has been reduced, and PS has no significant effect on the occurrence of ROP in premature infants.