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目的评估采用一种新型血栓抽吸(PT)装置DIVERTMCE导管在急性心肌梗死(AMI)经皮冠状动脉介入治疗(PCI)中的可行性、安全性及有效性。方法发病12h内的AMI病人42例,均行急诊PCI治疗,其中单纯PCI组23例,PCI+PT组19例,比较两组术后冠脉血流灌注水平(TIMI分级)、心肌血流灌注水平(TMP分级)及30d的主要不良心脏事件(MACE)。结果PCI+PT组术后平均罪犯血管TIMI血流恢复至(2.74±0.56)级,明显优于单纯PCI组[(2.30±0.63)级,P<0.05];PCI+PT组心肌灌注TMP分级(2.53±0.61)级,明显优于单纯PCI组[(2.13±0.55)级,P<0.05];30d内的MACE发生率两组间无显著性差异。结论在AMI患者急诊PCI治疗中运用血栓抽吸装置DIVERTMCE导管是安全、有效的,其疗效明显优于单纯PCI术。
Objective To evaluate the feasibility, safety and efficacy of DIVERTMCE catheter using a new thrombus aspiration (PT) device in percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Methods Forty-two AMI patients within 12 hours after onset were enrolled in the emergency PCI. Twenty-three patients in the PCI group and 19 patients in the PCI + PT group were included in this study. Coronary flow perfusion (TIMI grade), myocardial perfusion Level (TMP grading) and major adverse cardiac events (MACE) at 30 days. Results After PCI + PT group, mean blood vessel TIMI blood flow recovered to (2.74 ± 0.56), which was significantly better than that of PCI group [(2.30 ± 0.63), P <0.05]; PCI + PT group myocardial perfusion TMP grade 2.53 ± 0.61), which was significantly better than that of the PCI group [(2.13 ± 0.55), P <0.05]. There was no significant difference in the incidence of MACE within 30 days between the two groups. Conclusion It is safe and effective to use DIVERTMCE thrombus aspiration device in the emergency PCI of AMI patients. The curative effect is superior to that of PCI alone.