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目的 :探讨子宫颈腺体异型增生 (EGD)的临床病理特征。方法 :对 16例子宫颈点活检的子宫颈腺体异型增生标本进行光镜观察及子宫颈细胞学检查 ,并对 8例病人进行随访。结果 :组织学共同特点表现为 :子宫颈腺体增生活跃 ,腺结构密集 ,新生小腺体增多 ,腺上皮呈乳头状或丛状突入腺腔 ,呈单层或假复层结构 ,腺上皮细胞出现异型性。子宫颈细胞学涂片 4例考虑子宫颈腺体异型增生 ,12例为良性变异。随访 8例 ,5例高级别腺体异型增生中 4例进展为子宫颈腺癌 ,3例低级别腺体异型增生中 1例进展为子宫颈腺癌。结论 :子宫颈腺体异型增生可能是子宫颈腺癌的癌前病变
Objective: To investigate the clinicopathological features of cervical dysplasia (EGD). Methods: 16 cases of cervical biopsy cervical gland dysplasia specimens were observed by light microscopy and cervical cytology, and 8 patients were followed up. Results: The histological common features were as follows: the cervical gland hyperplasia was active, the glandular structure was dense, the small gonad increased, the glandular epithelium was papillary or plexiform protruding into the glandular cavity with single or pseudostratified structure, glandular epithelial cells Atypical. Cervical cytology smear in 4 cases considered dysplasia of cervical gland, 12 cases of benign variation. Follow-up 8 cases, 5 cases of high-grade gland dysplasia in 4 cases of progress for cervical adenocarcinoma, 3 cases of low-grade gland dysplasia in 1 case of progress for cervical adenocarcinoma. Conclusion: The dysplasia of cervical gland may be a precancerous lesion of cervical adenocarcinoma