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伴钙化与囊变的脑白质病(leukoencephalopathy,brain calcifications and cysts,LCC)临床较少见,发病机制尚未完全阐明,病理特征包括病变区脑组织小血管扩张、微血管出现血管瘤样重排、血管和脑实质发生钙化、胶质细胞增生等。本文结合1例LCC患者的诊疗过程,总结其临床表现及MRI影像特征。患者,女,43岁,以“右侧肢体无力,伴头痛、恶心进行性加重3个月”为主诉于2015年6月10日收入本院。患者3个月前无明显诱因出现右侧下肢无力,
The clinical manifestations of leukoencephalopathy (LCC) with calcification and cystic degeneration are rare, and the pathogenesis has not yet been fully elucidated. The pathological features include small blood vessel dilatation of brain tissue in lesion area, hemangio-reheat microangiopathy, And calcification occurs in the parenchyma, gliacyte and so on. This article combines the diagnosis and treatment of a case of LCC patients, summarizes its clinical manifestations and MRI imaging features. The patient, female, 43 years old, was admitted to our hospital on June 10, 2015 due to the “limb weakness with headache and nausea progressive aggravating for 3 months.” Patients 3 months ago no obvious incentive to appear on the right lower extremity weakness,