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目的探讨奥美拉唑联合莫沙必利治疗反流性食管炎的疗效。方法 78例患者随机分为治疗组和对照组,每组39例。治疗组服用奥美拉唑肠溶胶囊,20～60mg/次,1～2次/d。晨起空腹吞服或早晚各1次,莫沙必利5mg,3次/d,餐前口服,疗程8周。对照组:雷尼替丁150mg,2次/d,餐前口服,莫沙必利5mg,3次/d,餐前口服,疗程8周。观察两组患者的治疗效果。结果治疗组治疗8周后疗效与对照组比较差异有统计学意义(u=2.9545,P<0.01)。结论奥美拉唑联合莫沙必利治疗反流性食管炎疗效确切。
Objective To investigate the curative effect of omeprazole combined with mosapride on reflux esophagitis. Methods 78 patients were randomly divided into treatment group and control group, 39 cases in each group. The treatment group taking omeprazole enteric-coated capsules, 20 ~ 60mg / time, 1 ~ 2 times / d. Morning fasting swallowed or morning and evening 1 times, mosapride 5mg, 3 times / d, meal before oral treatment for 8 weeks. Control group: ranitidine 150mg, 2 times / d, pre-meal orally, mosapride 5mg, 3 times / d, pre-meal oral treatment for 8 weeks. Observed the treatment effect of two groups of patients. Results After 8 weeks treatment, the curative effect in the treatment group was significantly different from that in the control group (u = 2.9545, P <0.01). Conclusion Omeprazole combined with mosapride in the treatment of reflux esophagitis is effective.