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目的研究兔眼缝线固定式后房型人工晶状体植入术后早期炎症反应中房水的细胞学动态变化。方法分为缝线固定人工晶状体植入术组;晶状体囊外摘出组;正常对照组。术后1、3、7和14天抽取房水计数白细胞总数及分类。结果缝线固定人工晶状体植入术组术后房水炎症细胞数明显高于单纯晶状体囊外摘出组。结论术后早期房水白细胞总数和嗜中性粒细胞增加可能与手术所致的机械性创伤及血房水屏障破坏有关;术后房水巨噬细胞增多可能是对人工晶状体材料的一种免疫反应。
Objective To study the cytological changes of aqueous humor in the early stage of inflammatory reaction after implantation of posterior chamber intraocular lens (IOL) in rabbits. Methods were divided into suture fixation intraocular lens implantation group; Extracapsular lens capsule group; normal control group. A total number of leukocytes and their classification were drawn on days 1, 3, 7 and 14 postoperatively. Results The number of aqueous humor cells in the suture-fixed intraocular lens implantation group was significantly higher than that of extracapsular cataract extraction group. Conclusions The total number of leukocytes and neutrophils in the aqueous humor after the operation may be related to the mechanical trauma caused by the operation and the destruction of the blood-water barrier. Postoperative atrial-macrophage increase may be an immune response to intraocular lens reaction.