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[目的]观察桑白皮汤联合西药治疗痰热郁肺型慢性阻塞性肺病疗效。[方法]使用随机平行对照方法,将100例住院患者按就诊顺序号法简单随机分为两组。对照组50例控制性氧疗、解痉与化痰、平喘以及抗感染等常规治疗。治疗组50例桑白皮汤(黄连3g,山栀6g,苏子、半夏制、苦杏仁各10g,桑白皮、黄芪、浙贝母各12g),2剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗10d为1疗程。观测临床症状、用力肺活量(FVC)、一秒用力呼气容积(FEV1)、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈8例,显效27例,有效13例,无效2例,总有效率96.00%。对照组痊愈4例,显效15例,有效24例,无效5例,总有效率86.00%。治疗组疗效优于对照组(P<0.05)。用力肺活量(FVC)、一秒用力呼气容积(FEV1)两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]桑白皮汤联合西药治疗痰热郁肺型慢性阻塞性肺病效果显著,无严重不良反应,值得推广。
[Objective] To observe the curative effect of mulberry white peel soup combined with western medicine on phlegm-heat type of lung disease with chronic obstructive pulmonary disease. [Methods] Using randomized parallel control method, 100 cases of inpatients were randomly divided into two groups according to the sequence number of attendance. The control group of 50 cases of controlled oxygen therapy, antispasmodic and phlegm, asthma and anti-infection and other conventional treatment. The treatment group, 50 cases of Morus alba soup (Coptis 3g, Gardenia 6g, Suzi, Pinellia, bitter almond 10g, Morus alba, Astragalus, Fritillaria 12g), 2 / d, decoction 200m L , Morning and evening oral; western medicine treatment with the control group. Continuous treatment of 10d for a course of treatment. Clinical symptoms, forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and adverse reactions were observed. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group recovered in 8 cases, markedly effective in 27 cases, effective in 13 cases, ineffective in 2 cases, the total effective rate was 96.00%. The control group recovered 4 cases, markedly effective in 15 cases, effective in 24 cases, ineffective in 5 cases, the total effective rate was 86.00%. The treatment group was better than the control group (P <0.05). FVC and FEV1 improved in both groups (P <0.05), and improvement in treatment group was better than that in control group (P <0.05). [Conclusion] Sangbubi decoction combined with Western medicine has obvious effect on treating pulmonary COPD with phlegm and heat, without serious adverse reaction, which is worth to be popularized.