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目的探讨布地奈德和沙丁胺醇联合雾化吸入治疗小儿支气管哮喘的临床疗效。方法 108例小儿支气管哮喘患儿,随机分为对照组和观察组,每组54例。对照组患儿给予常规对症治疗,观察组在对照组治疗基础上给予布地奈德和沙丁胺醇联合雾化吸入治疗。对比两组患儿治疗后的临床疗效。结果观察组治疗总有效率为92.6%,对照组总有效率为77.8%,观察组总有效率高于对照组,差异有统计学意义(P<0.05);观察组咳嗽、喘憋、肺部哮鸣音及湿性啰音的消失时间均较对照组短,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论布地奈德和沙丁胺醇联合雾化吸入治疗小儿支气管哮喘,临床疗效显著,值得临床推广。
Objective To investigate the clinical efficacy of budesonide combined with albuterol inhalation in the treatment of pediatric bronchial asthma. Methods A total of 108 children with bronchial asthma were randomly divided into control group and observation group, with 54 cases in each group. The control group of children given conventional symptomatic treatment, the observation group was given budesonide and salbutamol combined with inhalation therapy on the basis of the control group. The clinical efficacy of two groups of children after treatment was compared. Results The total effective rate was 92.6% in the observation group and 77.8% in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The cough, wheezing, lung Wheezing and wet rales disappeared shorter than the control group, the difference was statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Budesonide and salbutamol inhalation combined with inhalation of bronchial asthma in children, the clinical efficacy is significant, worthy of clinical promotion.