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本文4例AATP发病年龄为3~11岁,均为女性,均经骨髓及血象检查排除再障、ITP及白前综合征等疾病。并参照国内外有关文献资料的诊断标准,确诊为AATP。本文有1例误诊为再障,3例误诊为ITP。3例病因不明,1例可能与发病前两周用阿鲁片及安乃近有关。本文4例病人均有皮肤出血点及瘀斑,2例鼻衄,1例因反复出血致缺铁性贫血。实验室检查:入院时检查1例有中度贫血,3例血色素正常。血小板计数19~38×10~9/L,网织红细胞计数0.5~2.2%。1例因合并上感致白细胞总数达13.4×10~9/L,中性80%,经抗感染治疗恢复正常。另外3例白细胞均在正常范围。骨髓涂片检查:均为骨髓增生活跃,1例粒系统比例增高达61.5%,1例红系比例增高达51.2%,各阶段细胞比例、形态均在正常范围。巨核细胞计数0~6个/片(2×3cm~2)。多次骨髓涂片检查无1例巨核细胞数恢复正常。治疗与转归:入院后均经强的松治疗:1例经强
In this paper, 4 cases of AATP onset age of 3 to 11 years old, were female, were excluded by the bone marrow and blood examination aplastic anemia, ITP and white-matter syndrome and other diseases. And with reference to the diagnostic criteria of domestic and foreign literature, diagnosed as AATP. This article has misdiagnosed as a case of aplastic anemia, 3 cases misdiagnosed as ITP. Three cases of unknown etiology, one case may be related to the two weeks before the onset of Aru tablets and metamizole. Four cases of patients in this paper, there are skin bleeding and ecchymosis, 2 cases of epistaxis, 1 case of iron deficiency anemia caused by repeated bleeding. Laboratory tests: 1 case admitted to moderate anemia, 3 cases of hemoglobin normal. Platelet count 19 ~ 38 × 10 ~ 9 / L, reticulocyte count 0.5 ~ 2.2%. One case of white blood cells caused by the merger of the total number of 13.4 × 10 ~ 9 / L, 80% neutral, anti-infective treatment returned to normal. The other three leukocytes were in the normal range. Bone marrow smear examination showed that all patients were active in bone marrow hyperplasia. The proportion of granulocyte in one case increased by 61.5% and the percentage of erythrocyte in one case increased by 51.2%. The proportion of cells in all stages and the morphology were in the normal range. Megakaryocyte count 0 ~ 6 / piece (2 × 3cm ~ 2). Multiple bone marrow smear examination without megakaryocyte number returned to normal. Treatment and outcome: After admission, prednisone treatment: one case by the strong